TRANSFORMER Knowledge Hub serves as a step-by-step advisory hub to build competence to regions and support the ecosystems of actors in evolving a cross-sectoral transition towards climate neutrality through innovation. Operating as a one-stop-shop, Knowledge Hub is composed of a portfolio of transition-enabling methodologies and tools from both the TRANSFORMER project and external sources that are structured along the phases and steps of the TRANSFORMER Transition Model and the roadmap to guide regions through the process of achieving a successful transition towards climate neutrality.